The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

维真生物的产品仅限用于研究，不可用于包括人类体外诊断和治疗在内的其他用途。

维真生物的产品，不得修改和转售给任何第三方，未经维真生物的书面批准，不得将产品用于向其他第三方提供服务或用于制造商品化产品。

使用本产品应遵守以上条款以及网站http://www.vigenebio.cn上的产品相关规定。您有责任阅读、了解并遵守这些条款所产生的任何限制。